Survival in metastatic ocular melanoma
نویسندگان
چکیده
منابع مشابه
Metastatic melanoma after 23 years of primary ocular melanoma
We describe a case of 52-year-old man who presented with an episode of tonic-clonic seizures. He had right ocular melanoma 23 years ago with subsequent enucleation which was the standard treatment at that time. CT scans of the brain and of the thorax-abdomen-pelvis revealed widespread metastatic lesions in the brain, lung and liver. Further investigations including bronchoscopy with cytopatholo...
متن کاملCirculating melanoma cells and survival in metastatic melanoma.
A validated assay for the enumeration of circulating melanoma cells (CMCs) may facilitate the development of more effective therapies for metastatic melanoma patients. In this study CD146+ cells were immunomagnetically enriched from 7.5 ml of blood. Isolated cells were fluorescently stained with DAPI, anti-molecular weight melanoma-associated antigen (HMW-MAA), anti-CD45 and CD34 and Ki67. CMCs...
متن کاملGermline BAP1 Inactivation Is Preferentially Associated with Metastatic Ocular Melanoma and Cutaneous-Ocular Melanoma Families
BACKGROUND BAP1 has been shown to be a target of both somatic alteration in high-risk ocular melanomas (OM) and germline inactivation in a few individuals from cancer-prone families. These findings suggest that constitutional BAP1 changes may predispose individuals to metastatic OM and that familial permeation of deleterious alleles could delineate a new cancer syndrome. DESIGN To characteriz...
متن کاملLong-term Survival after Metastatic Childhood Melanoma
SUMMARY Malignant melanoma in children is very rare and accounts for only 1-3% of all melanomas. A congenital melanocytic nevus depending on the size of the lesion is one of the risk factors for developing childhood melanoma because of the possible malignant transformation. Childhood malignant melanoma is a potentially fatal disease. Surgical excision is the primary treatment of choice for mali...
متن کاملRemission of Stage IV Metastatic Ocular Melanoma to the Liver
Introduction Ocular melanoma is characterized by a high rate of liver metastases. The median survival time is less than five months. There is no standard allopathic therapy for this condition. Although therapies based on the treatments of metastatic cutaneous melanoma have been tried, the conventional treatment of intravenous and intra-arterial hepatic infusions are usually futile. Systemic che...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Cancer
سال: 1983
ISSN: 0008-543X,1097-0142
DOI: 10.1002/1097-0142(19830715)52:2<334::aid-cncr2820520225>3.0.co;2-e